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CBX1

chromobox homolog 1

Synonymes:
CBX, HP1-BETA, HP1Hs-beta, HP1Hsbeta, M31, MOD1, p25beta
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(10951) Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(12412) chromobox 1
  • Rat(360609) chromobox homolog 1
  • naked mole-rat(101706928) chromobox homolog 1
  • domestic guinea pig(100716439) chromobox homolog 1
  • sheep(101116158) chromobox homolog 1
  • chicken(374237) chromobox homolog 1
  • domestic cat(101084070) chromobox homolog 1
  • cow(616506) chromobox homolog 1
  • dog(491051) chromobox homolog 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Heterochromatin Protein-1 β Antibody, clone 1MOD-1A9, ascites fluid, clone 1MOD-1A9, Chemicon®,
Espèces réactives
human, mouse
Application
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-CBX1 (HP1 beta) Antibody, clone 5E9.1, clone 5E9.1, from mouse,
Espèces réactives
human
Application
western blot
Anti-CBX1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, horse, human, mouse, pig, rabbit, rat, yeast
Application
western blot
Anti-CBX1 Antibody, clone 1D7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, canine, feline, human, monkey, mouse, porcine, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-CBX1/HP1-β antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
canine, human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CBX1,
Espèce(s)
human