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Merck

BUB1B

BUB1 mitotic checkpoint serine/threonine kinase B

Synonymes:
BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1
Espèce(s):
Human BUB1B (701), Mouse Bub1b (12236), Rat Bub1b (171576), sheep BUB1B (101108313), domestic guinea pig Bub1b (100728730), naked mole-rat Bub1b (101705847), chicken BUB1B (378922), dog BUB1B (608350), domestic cat BUB1B (101087670), cow BUB1B (537027)
ID UniProtKB:
O60566, B2R6U0, B4DL09, B4DLG3, O60501, O60627, O60758, O75389
ID du gène:
  • Human(701) Summary: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
  • Mouse(12236) budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
  • Rat(171576) BUB1 mitotic checkpoint serine/threonine kinase B
  • sheep(101108313) budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • domestic guinea pig(100728730) BUB1 mitotic checkpoint serine/threonine kinase B
  • naked mole-rat(101705847) BUB1 mitotic checkpoint serine/threonine kinase B
  • chicken(378922) budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • dog(608350) budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • domestic cat(101087670) budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • cow(537027) budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • Horse(100629735) budding uninhibited by benzimidazoles 1 homolog beta (yeast)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
MAB3612
Anti-BubR1 Antibody, clone 8G1, clone 8G1, Chemicon®, from mouse,
Espèces réactives
human
Application
immunocytochemistry
western blot
SAB4502941
Anti-BUB1B antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
western blot
WH0000701M2
Monoclonal Anti-BUB1B antibody produced in mouse, clone 2G5, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry
proximity ligation assay
western blot
ZRB2528
Anti-BubR1 Antibody, clone 1D23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
flow cytometry
immunohistochemistry
western blot
SAB1400031
Monoclonal Anti-BUB1B antibody produced in mouse, clone 3F2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
SRP5327
BUB1B, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHU052101
MISSION® esiRNA, targeting human BUB1B,
Espèce(s)
human