BACE1
beta-site APP-cleaving enzyme 1
Synonymes:
ASP2, BACE, HSPC104
Espèce(s):
Human BACE1 (23621), Mouse Bace1 (23821), Rat Bace1 (29392), Zebrafish bace1 (403005), cow BACE1 (614333), Horse BACE1 (100071137), domestic cat BACE1 (101086840), dog BACE1 (489390), chicken BACE1 (419768), sheep BACE1 (101119667) ...Plus
ID UniProtKB:
ID du gène:
- Human(23621) Summary: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
- Mouse(23821) beta-site APP cleaving enzyme 1
- Rat(29392) beta-site APP cleaving enzyme 1
- Zebrafish(403005) beta-site APP-cleaving enzyme 1
- cow(614333) beta-site APP-cleaving enzyme 1
- Horse(100071137) beta-site APP-cleaving enzyme 1
- domestic cat(101086840) beta-site APP-cleaving enzyme 1
- dog(489390) beta-site APP-cleaving enzyme 1
- chicken(419768) beta-site APP-cleaving enzyme 1
- sheep(101119667) beta-site APP-cleaving enzyme 1
- Domestic Rabbit(100343442) beta-site APP-cleaving enzyme 1
- naked mole-rat(101701890) beta-site APP-cleaving enzyme 1
- domestic guinea pig(100135485) beta-site APP cleaving enzyme 1
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ELISA
Référence du produit
Description
Espèce(s)
Activity Assay
Référence du produit
Description
Espèce(s)
β-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
Espèce(s)
human
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-BACE1 Antibody, clone 3D5, ,
Espèces réactives
human, mouse
Application
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-BACE Antibody, CT, clone 61-3E7, clone 61-3E7, Chemicon®, from mouse,
Espèces réactives
human, mouse, primate, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
microarray
western blot
western blot
Anti-BACE1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Kits
Référence du produit
Description
Espèce(s)
β-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
Espèce(s)
human
Proteins
Référence du produit
Description
Espèce(s)
β-Secretase human, recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), extracellular domain, ≥10,000 units/mg protein, ≥90% (SDS-PAGE), buffered aqueous solution,
Espèce(s)
human