APC
adenomatous polyposis coli
Synonymes:
BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
Espèce(s):
Human APC (324), Mouse Apc (11789), Rat Apc (24205), sheep APC (101104664), domestic guinea pig Apc (100723694), naked mole-rat Apc (101704055), Zebrafish apc (386762), fruit fly Apc (44642), cow APC (533233), Horse APC (100064431) ...Plus
ID UniProtKB:
ID du gène:
- Human(324) Summary: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
- Mouse(11789) adenomatosis polyposis coli
- Rat(24205) adenomatous polyposis coli
- sheep(101104664) adenomatous polyposis coli
- domestic guinea pig(100723694) adenomatous polyposis coli
- naked mole-rat(101704055) adenomatous polyposis coli
- Zebrafish(386762) adenomatosis polyposis coli
- fruit fly(44642) APC-like
- cow(533233) adenomatous polyposis coli
- Horse(100064431) adenomatous polyposis coli
- domestic cat(101096138) adenomatous polyposis coli
- dog(479139) adenomatous polyposis coli
- chicken(415607) adenomatous polyposis coli
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-APC Antibody, clone CC-1, clone CC-1, from mouse,
Espèces réactives
human
Application
immunohistochemistry
Anti-APC antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APC (Ab-1) Mouse mAb (FE9), liquid, clone FE9, Calbiochem®,
Espèces réactives
human, mouse, rat
Application
Anticorps anti-APC, clone FE9, clone FE9, from mouse,
Espèces réactives
human
Application
western blot
Anti-APC (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Cell Lines
Référence du produit
Description
Espèce(s)