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Merck

ANAPC5

anaphase promoting complex subunit 5

Synonymes:
APC5
Espèce(s):
Human ANAPC5 (51433), Mouse Anapc5 (59008), Rat Anapc5 (288671), Zebrafish anapc5 (322854), cow ANAPC5 (540537), Horse ANAPC5 (100058548), dog ANAPC5 (477471), chicken ANAPC5 (416842), sheep ANAPC5 (101102840), Domestic Rabbit ANAPC5 (100350286) ...Plus
ID UniProtKB:
Q9UJX4, E9PFB2, Q8N4H7, Q9BQD4
ID du gène:
  • Human(51433) Summary: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
  • Mouse(59008) anaphase-promoting complex subunit 5
  • Rat(288671) anaphase-promoting complex subunit 5
  • Zebrafish(322854) anaphase promoting complex subunit 5
  • cow(540537) anaphase promoting complex subunit 5
  • Horse(100058548) anaphase promoting complex subunit 5
  • dog(477471) anaphase promoting complex subunit 5
  • chicken(416842) anaphase promoting complex subunit 5
  • sheep(101102840) anaphase promoting complex subunit 5
  • Domestic Rabbit(100350286) anaphase promoting complex subunit 5
  • domestic guinea pig(100726899) anaphase promoting complex subunit 5
  • naked mole-rat(101724399) anaphase promoting complex subunit 5

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Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA039457
Anti-ANAPC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
HPA039801
Anti-ANAPC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
SAB3500151
Anti-APC5 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
EHU069691
MISSION® esiRNA, targeting human ANAPC5,
Espèce(s)
human
EMU069201
MISSION® esiRNA, targeting mouse Anapc5,
Espèce(s)
mouse