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ABCG8

ATP-binding cassette, sub-family G (WHITE), member 8

Synonymes:
GBD4, STSL
Espèce(s):
Human ABCG8 (64241), Mouse Abcg8 (67470), Rat Abcg8 (155192), domestic guinea pig Abcg8 (100725586), naked mole-rat Abcg8 (101723060), sheep ABCG8 (101113666), Domestic Rabbit ABCG8 (100350554), Zebrafish abcg8 (100136850), chicken ABCG8 (421402), cow ABCG8 (508829) ...Plus
ID UniProtKB:
Q9H221, Q53QN8
ID du gène:
  • Human(64241) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
  • Mouse(67470) ATP-binding cassette, sub-family G (WHITE), member 8
  • Rat(155192) ATP-binding cassette, subfamily G (WHITE), member 8
  • domestic guinea pig(100725586) ATP-binding cassette, sub-family G (WHITE), member 8
  • naked mole-rat(101723060) ATP-binding cassette, sub-family G (WHITE), member 8
  • sheep(101113666) ATP-binding cassette, sub-family G (WHITE), member 8
  • Domestic Rabbit(100350554) ATP-binding cassette, sub-family G (WHITE), member 8
  • Zebrafish(100136850) ATP-binding cassette, sub-family G (WHITE), member 8
  • chicken(421402) ATP-binding cassette, sub-family G (WHITE), member 8
  • cow(508829) ATP-binding cassette, sub-family G (WHITE), member 8
  • Horse(100069071) ATP-binding cassette, sub-family G (WHITE), member 8
  • domestic cat(101099288) ATP-binding cassette, sub-family G (WHITE), member 8
  • dog(474571) ATP-binding cassette, sub-family G (WHITE), member 8

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Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA019556
Anti-ABCG8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
MABS2054
Anti-ABCG8 Antibody, clone 1B10A5, clone 1B10A5, from mouse,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot