M003

R-(−)-Deprenyl hydrochloride

powder, ≥98% (HPLC)

• Synonym(s): (R)-(−)-N,α-Dimethyl-N-(2-propynyl)phenethylamine hydrochloride, R(−)-N-α-Dimethyl-N-2-propynyl-benzeneethanamine hydrochloride, Selegiline hydrochloride
• Empirical Formula (Hill Notation): C₁₃H₁₇N · HCl
• CAS Number: 14611-52-0
• Molecular Weight: 223.74
• MDL number: MFCD00069299
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278577
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]25/D −10.8°, c = 6.48 in H₂O(lit.)
• color: white
• mp: 141-142 °C
• solubility: H₂O: >10 mg/mL
• originator: Sanofi Aventis
• SMILES string: Cl[H].C[C@H](Cc1ccccc1)N(C)CC#C
• InChI: 1S/C13H17N.ClH/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13;/h1,5-9,12H,10-11H2,2-3H3;1H/t12-;/m1./s1
• InChI key: IYETZZCWLLUHIJ-UTONKHPSSA-N
• Gene Information: human ... MAOB(4129)

Description

Biochem/physiol Actions

Selective MAO-B inhibitor; anti-Parkinsonian agent.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H336
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves