311204
NG,NG′-Dimethyl-L-arginine, Dihydrochloride
Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.
Synonym(s):
NG,NG′-Dimethyl-L-arginine, Dihydrochloride, SDMA, 2HCl
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About This Item
Empirical Formula (Hill Notation):
C8H18N4O2 · 2HCl
Molecular Weight:
275.18
UNSPSC Code:
12352209
Recommended Products
Quality Level
Assay
≥97% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
color
white to light yellow
solubility
water: 50 mg/mL
shipped in
wet ice
storage temp.
2-8°C
General description
A cell-permeable endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.
Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
NOS in vitro
NOS in vitro
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Standard Handling (A)
Other Notes
Nam, S.W., et al. 1998. Arch. Pharm. Res. 21, 128.
Closs, E.I., et al. 1997. Nitric Oxide 1, 65.
Kotani, K., et al. 1992. J. Neurochem.58, 1127.
Closs, E.I., et al. 1997. Nitric Oxide 1, 65.
Kotani, K., et al. 1992. J. Neurochem.58, 1127.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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