860550P

Biotin Sphingosine

Avanti Polar Lipids 860550P, powder

• Synonym(s): omega-biotinyl D-erythro-sphingosine
• Empirical Formula (Hill Notation): C₂₈H₅₂N₄O₄S
• CAS Number: 752987-57-8
• Molecular Weight: 540.80
• UNSPSC Code: 12352211

Properties

• form: powder
• packaging: pkg of 1 × 1 mg (860550P-1mg)
• manufacturer/tradename: Avanti Polar Lipids 860550P
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@]1(CCCCC(NCCCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@](N)([H])CO)=O)SC[C@@]2([H])[C@]1([H])NC(N2)=O
• InChI: 1S/C28H52N4O4S/c29-22(20-33)24(34)16-12-10-8-6-4-2-1-3-5-7-9-11-15-19-30-26(35)18-14-13-17-25-27-23(21-37-25)31-28(36)32-27/h12,16,22-25,27,33-34H,1-11,13-15,17-21,29H2,(H,30,35)(H2,31,32,36)/b16-12+/t22-,23-,24+,25-,27-/m0/s1
• InChI key: NYQVYZZGZCNEMF-RPRIXWAOSA-N

Description

General description

Biotin Sphingosine is a derivative of sphingosine. It contains a biotin moiety linked to the ω-terminal of its fatty-acid chain.

Application

Biotin Sphingosine has been used as a substrate in sphingosine kinases (SphK) assay. It has also been used to label wt- ceramide synthase 1 (CerS1) expressed in UM-SCC-22A cells, to study the interaction between CerS1-generated C₁₈-ceramide and light chain 3 β (LC3B).

Biochem/physiol Actions

Biotin Sphingosineplays a vital role in identifying sphingosine interaction with acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A).

Packaging

5 mL Amber Glass Screw Cap Vial (860550P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3