850315P

08:0 PC

1,2-dioctanoyl-sn-glycero-3-phosphocholine, powder

• Synonym(s): PC(8:0/8:0)
• Empirical Formula (Hill Notation): C₂₄H₄₈NO₈P
• CAS Number: 19191-91-4
• Molecular Weight: 509.61
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 200 mg (850315P-200mg); pkg of 1 × 25 mg (850315P-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850315P
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC)=O)COC(CCCCCCC)=O)=O

Description

General description

Phosphatidylcholine (PC) is one of the most important constituent of the mucosal layer of the colon. 08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine/C8PC) is a water soluble short alkyl chain lipid.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine/C8PC) has been used as a substrate to study the analytical capabilities of several methods to determine water soluble phospholipids containing choline (wCh-PL) and also to study the behavior of the its analytical signal in a synthetic serum matrix (data-Trol). It may also be used as a bicellar model to study their phase behavior and to form a lipid film to study its effect on P-glycoprotein′s (P-gp′s) activity/to compare its effect with TWEEN^®80 and Cremophor^®EL.

Biochem/physiol Actions

Phosphatidylcholine (PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.

Packaging

20 mL Clear Glass Screw Cap Vial (850315P-200mg)

5 mL Clear Glass Sealed Ampule (850315P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Cremophor is a registered trademark of BASF SE

TWEEN is a registered trademark of Croda International PLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable