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SELPLG

selectin P ligand

Synonyms:
CD162, CLA, PSGL-1, PSGL1
Species:
Human SELPLG (6404), Mouse Selplg (20345), Rat Selplg (363930), cow SELPLG (617434), sheep SELPLG (101102589), naked mole-rat Selplg (101713908), domestic guinea pig Selplg (100712957), Zebrafish selplg (100884146), chicken SELPLG (772212), dog SELPLG (611673) ...More
UniProtKB ID:
Q14242, A8K2Y0, B4DQC3, B7Z5C7, J3KMX6, Q12775, Q6GTW7, Q8N7J7
Gene ID:
  • Human(6404) Summary: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
  • Mouse(20345) selectin, platelet (p-selectin) ligand
  • Rat(363930) selectin P ligand
  • cow(617434) selectin P ligand
  • sheep(101102589) selectin P ligand
  • naked mole-rat(101713908) selectin P ligand
  • domestic guinea pig(100712957) selectin P ligand
  • Zebrafish(100884146) selectin P ligand
  • chicken(772212) selectin P ligand
  • dog(611673) selectin P ligand
  • Horse(100034025) selectin P ligand
  • domestic cat(101087945) selectin P ligand

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ELISA

Product Number
Description
Species
RAB1651
Human PSGL-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
MAB4092
Anti-P-Selectin Glycoprotein Ligand-1 Antibody, clone KPL-1, clone KPL-1, Chemicon®, from mouse,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
MABF3036
Anti-PSGL-1/CD162 Antibody, clone HECA-452, ,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
western blot
HPA011256
Anti-Selplg Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
HPA069062
Anti-SELPLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
ZMS1199
Anti-PSGL-1/CD162 Antibody, clone KPL-1 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU160621
MISSION® esiRNA, targeting human SELPLG,
Species
human
EMU050221
MISSION® esiRNA, targeting mouse Selplg,
Species
mouse