P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
Synonyms:
P2Y6
Species:
Human P2RY6 (5031), Mouse P2ry6 (233571), Rat P2ry6 (117264), domestic guinea pig P2ry6 (100712612), naked mole-rat P2ry6 (101719811), sheep P2RY6 (101123660), chicken P2RY6 (396114), cow P2RY6 (539703), domestic cat P2RY6 (101099073), dog P2RY6 (485202)
UniProtKB ID:
Gene ID:
- Human(5031) Summary: The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Mar 2013]
- Mouse(233571) pyrimidinergic receptor P2Y, G-protein coupled, 6
- Rat(117264) pyrimidinergic receptor P2Y, G-protein coupled, 6
- domestic guinea pig(100712612) pyrimidinergic receptor P2Y, G-protein coupled, 6
- naked mole-rat(101719811) pyrimidinergic receptor P2Y, G-protein coupled, 6
- sheep(101123660) pyrimidinergic receptor P2Y, G-protein coupled, 6
- chicken(396114) pyrimidinergic receptor P2Y, G-protein coupled, 6
- cow(539703) pyrimidinergic receptor P2Y, G-protein coupled, 6
- domestic cat(101099073) pyrimidinergic receptor P2Y, G-protein coupled, 6
- dog(485202) pyrimidinergic receptor P2Y, G-protein coupled, 6
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Small Molecule - Agonist
Product Number
Description
Species
Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae, 95-100%,
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate, solid, ≥98% (HPLC),
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-P2Y6 Receptor Antibody, Chemicon®, from rabbit,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
immunohistochemistry
Anti-P2RY6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Purinergic Receptor P2Y6 Antibody, clone 4I8C9, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot
Anti-P2RY6 / P2Y6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, hamster, human, monkey, pig, rabbit, rat
Application
immunohistochemistry