NEFL
neurofilament, light polypeptide
Synonyms:
CMT1F, CMT2E, NF-L, NF68, NFL
Species:
Human NEFL (4747), Mouse Nefl (18039), Rat Nefl (83613), chicken NEFL (419528), cow NEFL (281348), domestic cat NEFL (101081039), dog NEFL (477378), naked mole-rat Nefl (101704332), domestic guinea pig Nefl (100731797), sheep NEFL (101119539)
UniProtKB ID:
Gene ID:
- Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
- Mouse(18039) neurofilament, light polypeptide
- Rat(83613) neurofilament, light polypeptide
- chicken(419528) neurofilament, light polypeptide
- cow(281348) neurofilament, light polypeptide
- domestic cat(101081039) neurofilament, light polypeptide
- dog(477378) neurofilament, light polypeptide
- naked mole-rat(101704332) neurofilament, light polypeptide
- domestic guinea pig(100731797) neurofilament, light polypeptide
- sheep(101119539) neurofilament, light polypeptide
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Neurofilament Antibodies Investigator Antibody Mini-Pack, anti-neurofilament H&M antibody, anti-neurofilament H antibody, and anti-neurofilament L antibody,
Species Reactivity
Application
Monoclonal Anti-Neurofilament 68 antibody produced in mouse, clone NR4, ascites fluid,
Species Reactivity
chicken, human, pig, rat
Application
immunohistochemistry
microarray
western blot
microarray
western blot
Anti-Neurofilament L Antibody, serum, Chemicon®,
Species Reactivity
bovine, canine, feline, human, mouse, pig, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Neurofilament L Antibody, clone 1E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-NEFL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Proteins
Product Number
Description
Species
esiRNA
Product Number
Description
Species