KEAP1
kelch-like ECH-associated protein 1
Synonyms:
INrf2, KLHL19
Species:
Human KEAP1 (9817), Mouse Keap1 (50868), Rat Keap1 (117519), fruit fly Keap1 (42062), cow KEAP1 (532791), dog KEAP1 (476713), domestic cat KEAP1 (101091260), sheep KEAP1 (101113845), domestic guinea pig Keap1 (100713871), naked mole-rat Keap1 (101718777)
UniProtKB ID:
Gene ID:
- Human(9817) Summary: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(50868) kelch-like ECH-associated protein 1
- Rat(117519) Kelch-like ECH-associated protein 1
- fruit fly(42062) CG3962 gene product from transcript CG3962-RC
- cow(532791) kelch-like ECH-associated protein 1
- dog(476713) kelch-like ECH-associated protein 1
- domestic cat(101091260) kelch-like ECH-associated protein 1
- sheep(101113845) kelch-like ECH-associated protein 1
- domestic guinea pig(100713871) kelch-like ECH-associated protein 1
- naked mole-rat(101718777) kelch-like ECH-associated protein 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-KEAP1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, human, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-KEAP1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-KEAP1, clone 7G4B10 Antibody, clone 7G4B10, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry
immunohistochemistry
flow cytometry
immunohistochemistry
Anti-KEAP1 Antibody, clone 3B9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
ELISA
affinity binding assay
immunocytochemistry
western blot
affinity binding assay
immunocytochemistry
western blot
Anti-KEAP1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Dimethyl Fumarate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Dimethyl fumarate, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human