Virus inactivation is critical in the purification of biotherapeutics. Triton X-100 is the most used detergent for virus inactivation in monoclonal antibodies, plasma industry, and bacterial cell lysis. However, Triton X-100 has been categorized as a hazardous chemical due to its strong endocrine effects after it biodegrades. It has gained attention and will be prohibited from manufacturing by the European Regulation (REACH). Considering REACH's recommendations and health concerns, MilliporeSigma has limited production of Triton X-100 with authorization from REACH and will discontinue over a period of time. To provide an alternative and help existing users of Triton X-100, we have developed Deviron C16, a sustainable product to replace Triton-X100. Deviron C16 has shown great performance and is as effective as Triton™ X-100 in the inactivation of viruses.
In this webinar, you will learn about:
- The major concerns with the use of Triton X-100
- Deviron C16 as a sustainable replacement to Triton X-100
- Virus inactivation in monoclonal antibodies and plasma industries using Deviron C16
Speaker
Sateesh Poojari
MilliporeSigma
Sr. Technical Application Expert
Satish has 17 years of experience in research, sales, sales development, field marketing, and technology management. He is an expert in cell line development, upstream process development using E. coli, and CHO platforms for expressing biotherapeutics and biosimilars. For the past 7 years, he has worked with the Technical University Munich, Hetero, Aurobindo, and others associated with MilliporeSigma, supporting our bioprocess business in India. Sateesh holds a double masters, one in biotechnology from Bangalore University and one in molecular biology from the University of Skovde, Sweden.
Pharma and biopharma manufacturing
- Monoclonal antibody manufacturing
Duration:42min
Language:English
Session 1:presented August 9, 2022
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