- Optical resolution of n-butyl D- and L-lactates using immobilized lipase catalyst.
Optical resolution of n-butyl D- and L-lactates using immobilized lipase catalyst.
Journal of bioscience and bioengineering (2010-09-21)
Hitomi Ohara, Masafumi Yamamoto, Akihisa Onogi, Koichi Hirao, Shiro Kobayashi
PMID20851671
RESUMO
n-Butyl D- and L-lactates (BuDLa and BuLLa) were incubated with immobilized lipase. (1)H-NMR showed that BuDLa reacted to oligomers, while BuLLa did not react. A mixture containing 90.4% of BuLLa and 9.6% of BuDLa was incubated with the enzyme for 72 h, then distilled. The purity of BuLLa increased to 98.6%.
MATERIAIS