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Documentos

1349626

USP

Isomalt

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

6-O-α-D-Glucopyranosyl-D-glucitol mixed with 1-O-α-D-glucopyranosyl-D-mannitol

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About This Item

Fórmula empírica (Notação de Hill):
C12H24O11
Número CAS:
Peso molecular:
344.31
Código UNSPSC:
41116107
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

isomalt

fabricante/nome comercial

USP

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

InChI

1S/C12H24O11/c13-1-4(15)7(17)8(18)5(16)3-22-12-11(21)10(20)9(19)6(2-14)23-12/h4-21H,1-3H2/t4?,5-,6-,7-,8-,9-,10+,11-,12+/m1/s1

chave InChI

SERLAGPUMNYUCK-BLEZHGCXSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Isomalt USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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D-Manitol ≥98% (GC)

Sigma-Aldrich

M4125

D-Manitol

D-sorbitol ≥98% (GC)

Sigma-Aldrich

S1876

D-sorbitol

Gerad K Bolhuis et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(3), 621-625 (2009-03-31)
Although other polyols have been described extensively as filler-binders in direct compaction of tablets, the polyol isomalt is rather unknown as pharmaceutical excipient, in spite of its description in all the main pharmacopoeias. In this paper the compaction properties of
F Ndindayino et al.
International journal of pharmaceutics, 189(1), 113-124 (1999-10-16)
Isomalt is a sugar substitute with a wide range of potential pharmaceutical applications as a result of its physicochemical properties. Four grades of this material were evaluated for their physical characteristics. Only Palatinit(R) C and F exhibited potential characteristics for
F Ndindayino et al.
International journal of pharmaceutics, 246(1-2), 199-202 (2002-09-25)
The bioavailability of hydrochlorothiazide (HCT) from moulded isomalt-based tablets was evaluated after oral administration of 50 mg HCT to healthy volunteers as an oral moulded tablet and as a lozenge, in comparison with a conventional tablet formulation (Dichlotride 50 mg).
G D Walker et al.
Caries research, 44(1), 33-40 (2010-01-22)
Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) has been demonstrated to exhibit anticariogenic activity in randomized, controlled clinical trials of sugar-free gum and a tooth cream. Two randomized, double-blind, crossover studies were conducted to investigate the potential of CPP-ACP added to hard
What clients need to know about sugar replacers.
K McNutt
Journal of the American Dietetic Association, 100(4), 466-469 (2000-04-18)

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