SCP0157

Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP)

• Sinônimo(s): GRGDSP Peptide, RGD Peptide
• Fórmula empírica (Notação de Hill): C₂₂H₃₇N₉O₁₀
• Peso molecular: 587.58
• Código UNSPSC: 12352209
• NACRES: NA.32

Propriedades

• Ensaio: ≥95% (HPLC)
• Formulário: lyophilized
• composição: Peptide Content, ≥60%
• condição de armazenamento: protect from light
• temperatura de armazenamento: −20°C

Descrição

Amino Acid Sequence

Gly-Arg-Gly-Asp-Ser-Pro

Descrição geral

Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is a bioactive molecule/peptide derived from fibronectin.

Aplicação

Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) has been used:

• in coating well plate to monitor cell attachment by crystal violet staining
• to treat baby hamster kidney (BHK-21) cells to study the role of Arg-Gly-Asp (RGD) motif in the replication of Japanese encephalitis virus (JEV)
• to block RGD-dependent integrins or integrin signaling in INA-6 cells
• to study the role of the RGD-binding integrins in Gal-3-mediated cell adhesion

Ações bioquímicas/fisiológicas

Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) can stimulate endothelialization by modifying the surface of cardiovascular implants. The major cell- binding domain of GRGDSP helps to promote cell adhesion on a wide range of substrates.

Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable