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Key Documents

SAB3501044

Sigma-Aldrich

Anti-TFEB antibody produced in rabbit

affinity isolated antibody

Sinônimo(s):

Anti-ALPHATFEB, Anti-BHLHE35, Anti-TCFEB

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

reatividade de espécies

human

concentração

1 mg/mL

técnica(s)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

nº de adesão NCBI

NP_009093

nº de adesão UniProt

P19484

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... TFEB(7942)

Imunogênio

Antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TFEB.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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C S Carr et al.
Molecular and cellular biology, 10(8), 4384-4388 (1990-08-01)
A human cDNA encoding a novel protein in the helix-loop-helix family has been isolated by screening a bacteriophage expression library with a probe containing the binding site for major late transcription factor. The protein encoded by this cDNA, TFEB, probably
Marco Sardiello et al.
Science (New York, N.Y.), 325(5939), 473-477 (2009-06-27)
Lysosomes are organelles central to degradation and recycling processes in animal cells. Whether lysosomal activity is coordinated to respond to cellular needs remains unclear. We found that most lysosomal genes exhibit coordinated transcriptional behavior and are regulated by the transcription
Ian J Davis et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(10), 6051-6056 (2003-04-30)
MITF, TFE3, TFEB, and TFEC comprise a transcription factor family (MiT) that regulates key developmental pathways in several cell lineages. Like MYC, MiT members are basic helix-loop-helix-leucine zipper transcription factors. MiT members share virtually perfect homology in their DNA binding
Randall Logan et al.
Journal of pharmaceutical sciences, 103(10), 3287-3296 (2014-07-22)
Many weakly basic amine-containing drugs are known to be extensively sequestered in acidic lysosomes by an ion trapping-type mechanism. The entrapment of drugs in lysosomes has been shown to influence drug activity, cancer cell selectivity, and pharmacokinetics and can cause

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