SAB1300556

Anti-NR6A1 (C-term) antibody produced in rabbit

Ig fraction of antiserum, buffered aqueous solution

• Sinônimo(s): Anti-GCNF, Anti-Germ cell nuclear factor, Anti-HGCNF, Anti-RTR, Retinoid receptor-related testis-specific receptor
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: Ig fraction of antiserum
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• reatividade de espécies: human
• técnica(s): indirect ELISA: 1:1000; western blot: 1:100-1:500
• nº de adesão NCBI: NP_201591
• nº de adesão UniProt: Q15406
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... NR6A1(2649)

Descrição

Descrição geral

NR6A1 has been shown to affect gene expression in embryogenesis and spermatogenesis and is essential for embryonic survival and normal development. Loss of NR6A1 causes embryonic lethality and disrupts normal somitogenesis as well as neural-tube and axis formation. NR6A1 binds as a homodimer to the DR0 DNA response element and has been shown to regulate transcription of genes including protamines 1 and 2 and Oct4. NR6A1 repression function has been shown to be mediated by interaction with the co-repressors N-COR and SMRT in the absence of ligand.

Imunogênio

NR6A1 (NP_201591, 340-375)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NR6A1.

forma física

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable