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S6635

Sigma-Aldrich

Span® 20

greener alternative

Sinônimo(s):

Sorbitan laurate, Sorbitan monolaurate

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About This Item

Número CAS:
1338-39-2
Número CE:
215-663-3
Número MDL:
MFCD00005365
Código UNSPSC:
12161900
ID de substância PubChem:
24899716
NACRES:
NA.25

descrição

non-ionic

peso molecular

346.47 g/mol

características do produto alternativo mais ecológico

Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

concentração

≥44% (GC)

categoria alternativa mais ecológica

, Aligned

cadeia de caracteres SMILES

CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C18H34O6/c1-2-3-4-5-6-7-8-9-10-11-16(21)23-13-15(20)18-17(22)14(19)12-24-18/h14-15,17-20,22H,2-13H2,1H3/t14-,15?,17+,18+/m0/s1

chave InChI

LWZFANDGMFTDAV-WYDSMHRWSA-N

Categorias relacionadas

Descrição geral

Span 20 is a co-surfactant.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is 100% bio-based non-ionic surfactant, thus aligns with "Use of Renewable Feedstocks" and belongs to "12 principles aligned" category of our greener alternatives.

Aplicação

Span 20 has been used in a study to assess enhanced solubility and oral bioavailability of itraconazole. It has also been used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions.

Outras notas

Fatty acid composition: Lauric acid (C12:0) ≥ 44%; balance primarily myristic (C14:0), palmitic (C16:0) and linolenic (C18:3) acids.

Informações legais

Span is a registered trademark of Croda International PLC

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

>300.2 °F - closed cup

Ponto de fulgor (°C)

> 149 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Claire Berton et al.
Journal of colloid and interface science, 377(1), 244-250 (2012-04-25)
The development of lipid oxidation in oil-in-water (O/W) emulsions is widely influenced by the properties of the interfacial layer, which separates the oil and water phases. In this work, the effect of the structure of the interface on the oxidative
Sinead Hickey et al.
International journal of pharmaceutics, 388(1-2), 213-222 (2009-12-17)
High-resolution ultrasonic spectroscopy was applied to analyse a pseudo-ternary phase diagram for a mixture consisting of water/ethyl oleate/Tween 80 and Span 20 at 25 degrees C. The measured changes in the ultrasonic velocity and attenuation with concentration of water in
Pao-Chu Wu et al.
Drug development and industrial pharmacy, 36(12), 1398-1403 (2010-06-16)
Nicardipine hydrochloride has been used widely for the treatment of angina pectoris and hypertension. Because of its extensive first pass metabolism after oral administration, the transdermal administration of nicardipine microemulsions was developed in this study. Microemulsions consisted of isopropyl myristate
Gabriela Calderó et al.
Journal of colloid and interface science, 353(2), 406-411 (2010-10-26)
Formation of polymeric O/W nano-emulsions has been studied in the water/polyoxyethylene 4 sorbitan monolaurate/ethylcellulose solution system by the phase inversion composition (PIC) method. These nano-emulsions were used for the preparation of nanoparticles by solvent evaporation. Composition variables such as O/S
Orapan Paecharoenchai et al.
Journal of drug targeting, 20(9), 783-792 (2012-08-31)
Non-ionic surfactant-based vesicles (niosomes) composed of non-ionic surfactants (i.e., Tween and Span) and cholesterol were formulated, and their turbidity and particle size assayed. The most appropriate niosomes formulation was mixed with novel synthesized spermine-based cationic lipids to prepare cationic niosomes
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