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RAB0257

Sigma-Aldrich

Mouse IL-13 ELISA Kit

for serum, plasma and cell culture supernatant

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.32

reatividade de espécies

mouse

embalagem

kit of 96 wells (12 strips x 8 wells)

técnica(s)

ELISA: suitable
capture ELISA: suitable

entrada

sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 8023-2000 pg/mL

método de detecção

colorimetric

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

Informações sobre genes

mouse ... Il13(16163)

Descrição geral

The Mouse IL-13 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IL-13 in serum, plasma, cell culture supernatants and urine.

Imunogênio

Recombinant Mouse IL-13

Aplicação

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Mouse IL-13 ELISA Kit has been used to measure the concentration of interleukin (IL)-13 in serological sampleand bronchoalveolar lavage fluids (BALFs).

Ações bioquímicas/fisiológicas

Interleukin 13 (IL13) is up-regulated during parasitic infections and participates in host′s protective immunity against Schistosoma japonicum. This protein promotes eosinophil activation resulting in elevated specific IgE against adult and larval antigens. During acute infection it promotes egg expulsion through increased intestinal contractility. It acts as a liver protective agent where it promotes the formation of liver granulomas in a CD4+ T cell-mediated manner, which results in liver fibrosis. In airway disorders, such as asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis lung disease, IL13 promotes the formation of airway goblet cells, resulting in excess mucus secretion, which in turn, is regulated by IL13-activated autophagy.

Outras notas

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Componentes do kit também disponíveis separadamente

Nº do produto
Descrição
SDS

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pictogramas

Corrosion

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Met. Corr. 1

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Visite a Biblioteca de Documentos

Therapeutic effects of liver soothing pingchuan formula decoction on experimental asthma in BALB/c mice via regulation of nerve growth factor-tyrosine kinase A pathway
Zhang XG, et al.
Molecular Medicine Reports, 17(5), 6977-6984 (2018)
Paeoniflorin targets apoptosis and ameliorates fibrosis in murine schistosomiasis mansoni: A novel insight
El-Aal N, et al.
Experimental Parasitology, 183, 23-32 (2017)
Xin-Guang Zhang et al.
Molecular medicine reports, 17(5), 6977-6984 (2018-03-24)
The present study was designed to investigate the effects of liver soothing pingchuan formula decoction (LSPF) on experimental asthma in BALB/c mice and explore its potential molecular mechanisms. An animal model of asthma was established in BALB/c mice through sensitization and activation with
Tae Young Jang et al.
International immunopharmacology, 22(2), 444-450 (2014-08-12)
To evaluate the antiallergic effects of oral benzaldehyde in a murine model of allergic asthma and rhinitis, we divided 20 female BALB/c mice aged 8-10 weeks into nonallergic (intraperitoneally sensitized and intranasally challenged to normal saline), allergic (intraperitoneally sensitized and
An IL-13 promoter polymorphism associated with liver fibrosis in patients with Schistosoma japonicum.
Long X et al
PLoS ONE, 10(8), e0135360-e0135360 (2015)

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