M5815

Monoclonal Anti-Myogenin antibody produced in mouse

clone F12B, purified immunoglobulin, buffered aqueous solution

• Número MDL: MFCD01322371
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 200
• conjugado: unconjugated
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: F12B, monoclonal
• forma: buffered aqueous solution
• peso molecular: antigen 34 kDa
• reatividade de espécies: mouse, rat, human
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1-2 μg/mL using rhabdomyosarcoma tissue sections; immunoprecipitation (IP): 2 μg using 1 mg protein lysate; indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1 μg/mL
• Isotipo: IgG1
• nº de adesão UniProt: P15173
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... MYOG(4656) ; mouse ... Myog(17928) ; rat ... Myog(29148)

Descrição

Descrição geral

Myogenin belongs to the basic helix-loop-helix (bHLH) superfamily.

Myogenin is a transcription factor present in the nucleus. It possesses an amino-acid rich region and a helix-loop-helix structure. The gene encoding it is localized on human chromosome 1q31-41 and has three exons.

Imunogênio

rat recombinant myogenin (amino acids 30-224).

Aplicação

Monoclonal Anti-Myogenin antibody produced in mouse has been used in immunohistochemistry, immunofluorescence and western blotting.

Ações bioquímicas/fisiológicas

Myogenin acts as a biomarker in rhabdomyosarcoma (RMS). It has a role in developmental processes, such as hematopoiesis, neurogenesis, myogenesis, tumor cell invasion and metastasis.

Myogenin acts as a regulator during myoblast and skeletal muscle differentiation. It is considered as a definite marker for skeletal muscle differentiation.

forma física

Solution in phosphate buffered saline containing 0.08% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable