GE11-0034-95

HiTrap^® MabSelect SuRe^™

Cytiva 11-0034-95, pack of 5 × 5 mL

• Sinônimo(s): prepacked columns, MabSelecT columns
• Código UNSPSC: 23151816
• NACRES: NA.56

Propriedades

• ligand: alkali-stabilized protein A-derived (E. coli)
• embalagem: pack of 5 × 5 mL
• fabricante/nome comercial: Cytiva 11-0034-95
• condição de armazenamento: (20% Ehtanol); (20% Ethanol)
• Parâmetros: flow rate; 42 psi
• tamanho do leito: 16 mm × 25 mm
• volume do leito: 5 mL
• D.I. da coluna: 16 mm
• matriz: highly cross-linked agarose
• Tamanho médio da partícula: 85 μm (d₅₀v is the median particle size of the cumulative volume distribution)
• cleaning: 2-13.7
• working range: 3-12
• capacidade: ≥30 mg binding capacity (humanlgG/ml at 2.4 min residence time)
• adequação: suitable for bioprocess medium
• temperatura de armazenamento: 2-8°C

Descrição

Descrição geral

Determined at 10% breakthrough by frontal analysis at a mobile phase velocity of 500 cm/h in a column with a bed height of 20 cm.

HiTrap^® MabSelect^™ SuRe
HiTrap^® MabSelect^™ SuRe^™ columns are prepacked with MabSelect^™ SuRe, a BioProcess medium for purification of monoclonal antibodies from large sample volumes. The novel alkali-tolerant recombinant Protein A ligand allow cleaning-in-place (CIP).

HiTrap^® MabSelect^™ columns are prepacked with MabSelect^™ a bioprocess medium for capuring of Mabs from large sample volumes.

Características e benefícios

• Withstands rigorous CIP and sanitization procedures with 0.1 to 0.5 M NaOH.
• Novel ligand design gives enhanced protease resistance resulting in lower ligand leakage.
• Oriented coupling of recombinant Protein A to the matrix via an engineered C-terminal cysteine enhances IgG binding capacity.
• Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification.
• Prepacked HiTrap^® columns for process development, screening of purification conditions, and small-scale purification of Mabs.

Armazenamento e estabilidade

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Nota de análise

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Outras notas

1)The pressure over the packed bed varies depending on a range of parameters such as the characteristics of the chromatography medium and the column tubing used.

The pressure over the packed bed varies depending on a range of parameters such as the characteristics of the chromatography medium and the column tubing used.

Informações legais

Free MabSelect SuRe Ligand
"MabSelect SuRe Ligand Restricted License" and "Cys-rProtein A Ligand Restricted License" are protected by the following patents and equivalent patents and patent applications in other countries: US 6,399,750 and EP 1123389. A free, non-transferable limited license to use this product for internal analytical purposes only accompanies the purchase of the product from a Cytiva company and its licensed distributors. Any other use will require a separate license from a Cytiva company.

HiTrap is a registered trademark of Cytiva

MabSelect is a trademark of Cytiva

MabSelect SuRe is a trademark of Cytiva

SuRe is a trademark of Cytiva

Informações de segurança

• Pictogramas: GHS02
• Palavra indicadora: Warning
• Frases de perigo: H226
• Declarações de precaução: P280 - P210 - P241 - P235 - P303 + P361 + P353 - P501
• Código de classe de armazenamento: 3 - Flammable liquids