F5012
Anti-Ferritin, Human antibody produced in rabbit
whole antiserum, liquid
Sinônimo(s):
Anti-FHC, Anti-FTH, Anti-FTHL6, Anti-HFE5, Anti-PIG15, Anti-PLIF
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About This Item
Produtos recomendados
fonte biológica
rabbit
conjugado
unconjugated
forma do anticorpo
whole antiserum
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
forma
liquid
contém
15 mM sodium azide
reatividade de espécies
human
técnica(s)
Ouchterlony double diffusion: 1:16
nº de adesão UniProt
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... FTH1(2495)
Descrição geral
Ferritin, an iron-storage protein is usually present in the liver and spleen in mammals. Iron and ferritin are distributed relatively same in the eye. Ferritin is made up of heavy and light chains.
Imunogênio
Ferritin isolated from normal human spleen
Aplicação
- Anti-Ferritin, Human antibody produced in rabbit has been used in:
- immunohistochemistry
- western blotting
- immunocytochemical techniques
Anti-Ferritin, Human antibody is suitable for use in Ouchterlony double diffusion (1:16 using human spleen ferritin), and immunoelectrophoresis. The antibody may also be used in western blot (1:1000 using frozen liver homogenates) and immunoprecipitation (using 300 μg of cell lysate incubated with 6 mul of anti-ferritin for 1h at 4 ° C).
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Ações bioquímicas/fisiológicas
Ferritin is an iron-storage protein that regulates iron-homeostasis in cells. While mitochondrial ferritin is a homopolymer, the cytosolic form consists of heteropolymeric L- and H-chains. Genetic mutations in ferritin L-chains have been associated with neurodegenerative disorders, whereas altered levels of ferritin have been linked to hemophagocytic lymphohistiocytosis and adult-onset Still′s disease . In immunoelectrophoresis, anti-ferritin, human antibody is specific for ferritin when used against human spleen extract and purified ferritin. No reactivity is observed against normal human serum.
Nota de preparo
The antiserum has been treated to remove lipoproteins.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
nwg
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
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Multipotent stem cells are thought to be responsible for the generation of new neurons in the adult brain. Neurogenesis also occurs in an accessible part of the nervous system, the olfactory mucosa. We show here that cells from human olfactory
Increased Iron Sequestration in Alveolar Macrophages in Chronic Obtructive Pulmonary Disease
Philippot Q, et al.
Testing, 9(5), e96285-e96285 (2014)
Altered expression of iron regulatory genes in cirrhotic human livers: clues to the cause of hemosiderosis
Bergmann OM, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 88(12), 1349-1357 (2008)
Scientific tests
Aldred EM, et al.
Pharmacology, 331-341 (2009)
Iron-Induced Retinal Damage
Handbook of nutrition, diet, and the eye, 619-626 (2014)
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