AV34590

Anti-METTL3 (AB1) antibody produced in rabbit

IgG fraction of antiserum

• Sinônimo(s): Anti-Methyltransferase like 3
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: IgG fraction of antiserum
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: 64 kDa
• reatividade de espécies: dog, human, bovine, goat, mouse, horse, rat, rabbit, guinea pig
• concentração: 0.5 mg - 1 mg/mL
• técnica(s): western blot: suitable
• nº de adesão NCBI: NP_062826
• nº de adesão UniProt: Q86U44
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... METTL3(56339)

Descrição

Descrição geral

Methyltransferase like 3 (METTL3 or M6A) codes for a 70 kDa subunit of MT-A. This protein forms a heterodimeric complex with METTL14 and modulates the methylation of the mammalian nuclear RNA, N6-adenosine.
Rabbit Anti-METTL3 antibody recognizes bovine, human, mouse, rat, zebrafish, and canine METTL3.

Imunogênio

Synthetic peptide directed towards the middle region of human METTL3

Aplicação

Rabbit Anti-METTL3 antibody is suitable for western blot applications at a concentration of 5 μg/ml.

Ações bioquímicas/fisiológicas

METTL3 is the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Sequência

Synthetic peptide located within the following region: AKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILELLNTTTA

forma física

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable