A9519

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate

≥98% (TLC), suitable for ligand binding assays

• Sinônimo(s): Adjuvant Peptide, Muramyl dipeptide
• Fórmula empírica (Notação de Hill): C₁₉H₃₂N₄O₁₁ · xH₂O
• Número CAS: 53678-77-6
• Peso molecular: 492.48 (anhydrous basis)
• Beilstein: 4220745
• Número CE: 258-696-9
• Número MDL: MFCD00077638
• Código UNSPSC: 12352209
• ID de substância PubChem: 24891464
• NACRES: NA.26

Propriedades

• product name: N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate, ≥98% (TLC)
• Ensaio: ≥98% (TLC)
• forma: powder
• técnica(s): ligand binding assay: suitable
• cor: white
• aplicação(ões): cell analysis
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: C[C@H](NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(C)=O)C(=O)N[C@H](CCC(O)=O)C(N)=O
• InChI: 1S/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19?/m0/s1
• chave InChI: BSOQXXWZTUDTEL-QAQREVAFSA-N

Descrição

Amino Acid Sequence

MurNAc-Ala-Agn

Aplicação

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate has been used in staphylococcal cell wall preparation to induce the release of TNF from human monocytes.

Ações bioquímicas/fisiológicas

Enhances antigenicity of weak antigens, increasing antibody titer.

Muramyl peptides are monomeric components that make up the bacterial cell wall peptidoglycan. It is generally produced by mammalian macrophages, as an immune response in the breakdown of bacterial cell wall. MDP promotes the production of interleukin-1 and tumor necrosis factor (TNF), which increase slow-wave sleep.

N-Acetylmuramyl-L-alanyl-D-isoglutamine (MDP, muramyl dipeptide), a neurotrophic and immunomodulatory factor related to bacterial peptidoglycans, is used as an immune modulation factor that enhances immune response and to study neural development.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)