A7505

1,4-Androstadiene-3,17-dione

• Sinônimo(s): 1-Dehydroandrostenedione, Androstadienedione
• Fórmula empírica (Notação de Hill): C₁₉H₂₄O₂
• Número CAS: 897-06-3
• Peso molecular: 284.39
• Número CE: 212-977-2
• Número MDL: MFCD00003614
• Código UNSPSC: 41116107
• ID de substância PubChem: 24891245
• NACRES: NA.77

Propriedades

• fonte biológica: synthetic (organic)
• Ensaio: ≥85% (HPLC)
• forma: powder
• controle de medicamentos: USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada
• solubilidade: chloroform: 50 mg/mL, clear, colorless to faintly yellow
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]4(C)C(=O)CC[C@@]24[H]
• InChI: 1S/C19H24O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-16H,3-6,8,10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
• chave InChI: LUJVUUWNAPIQQI-QAGGRKNESA-N
• Informações sobre genes: human ... CYP19A1(1588)

Descrição

Descrição geral

1,4-Androstadiene-3,17-dione is a 17-keto anabolic steroid.

Ações bioquímicas/fisiológicas

1,4-Androstadiene-3,17-dione is a prohormone that converts to an active steroid through the 17bHSD enzyme. 1,4-Androstadiene-3,17-dione is a metabolite of progesterone.

1,4-Androstadiene-3,17-dione is useful in forming pharmaceutically important steroids. Regio- and stereospecific hydroxylation of 1,4-androstadiene-3,17-dione increases its biological activity. Its derivative is also used to produce high-value bile acids. 1,4-Androstadiene-3,17-dione serves as a precursor for the synthesis of progesterone, testosterone, cortisol, estradiol, cortisone, prednisolone, and prednisone.