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322M-1

Podoplanin (D2-40) Mouse Monoclonal Antibody

Name: Podoplanin (D2-40) Mouse Monoclonal Antibody
Brand: SIGMA

clone D2-40, unconjugated, Cell Marque^™

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About This Item

Código UNSPSC:

12352203

NACRES:

NA.41

fonte biológica

mouse

Nível de qualidade

100
500

conjugado

unconjugated

forma do anticorpo

culture supernatant

tipo de produto de anticorpo

primary antibodies

clone

D2-40, monoclonal

descrição

For In Vitro Diagnostic Use in Select Regions (See Chart)

forma

buffered aqueous solution

reatividade de espécies

human

embalagem

vial of 0.1 mL concentrate (322M-14)
vial of 0.5 mL concentrate (322M-15)
bottle of 1.0 mL predilute (322M-17)
vial of 1.0 mL concentrate (322M-16)
bottle of 7.0 mL predilute (322M-18)

fabricante/nome comercial

Cell Marque^™

técnica(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:20-1:100

Isotipo

IgG1

controle

tonsil

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

visualização

cytoplasmic

Informações sobre genes

human ... PDPN(10630)

Descrição geral

Podoplanin is a transmembrane mucoprotein (38 kD) recognized by the D2-40 monoclonal antibody. Podoplanin is selectively expressed in normal and malignant lymphatic endothelium, including Kaposi’s sarcomas. Podoplanin has also been shown to be expressed in epithelioid mesotheliomas and seminomas.

Qualidade

IVD

RUO

Ligação

Podoplanin Positive Control Slides, Product No. 322S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Identification of lymphatic vessels in malignant, adenomatous and normal colonic mucosa using the novel immunostain D2-40.

F Fogt et al.

Oncology reports, 11(1), 47-50 (2003-12-05)

Distribution of lymphatic vessels in normal and neoplastic colon has been previously analyzed with electron microscopic techniques, as reliable antibodies have not been available for selective lymph vessel staining. A novel monoclonal antibody, D2-40, is recently available to differentiate lymphatic

Detection of lymphatic invasion in primary melanoma with monoclonal antibody D2-40: a new selective immunohistochemical marker of lymphatic endothelium.

Firouzeh Niakosari et al.

Archives of dermatology, 141(4), 440-444 (2005-04-20)

To identify the presence of lymphatic invasion in primary cutaneous melanoma using monoclonal antibody D2-40, a marker of lymphatic endothelium, and to correlate the presence of lymphatic invasion with other clinicopathologic characteristics of the tumors. Retrospective melanoma case series study

Utility of D2-40, a novel mesothelial marker, in the diagnosis of malignant mesothelioma.

Albert Y Chu et al.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 18(1), 105-110 (2004-09-25)

Although immunohistochemistry has proven to be valuable in the differentiation of epithelioid mesothelioma from pulmonary or metastatic adenocarcinoma, no single antibody has demonstrated absolute sensitivity or specificity in making this distinction. Using immunohistochemical analysis with D2-40, a recently available monoclonal

Hobnail hemangiomas (targetoid hemosiderotic hemangiomas) are true lymphangiomas.

Folker E Franke et al.

Journal of cutaneous pathology, 31(5), 362-367 (2004-04-03)

Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a small benign vascular tumor of the superficial and mid-dermis. In contrast to its well-characterized histology, it has been unclear whether this tumor arises from blood vessel endothelial cells (BECs) or lymphatic vessel endothelial

Podoplanin: a novel diagnostic immunohistochemical marker.

Nelson G Ordóñez

Advances in anatomic pathology, 13(2), 83-88 (2006-05-04)

Podoplanin is a transmembrane mucoprotein recognized by the recently commercially available D2-40 monoclonal antibody. Recent investigations have shown that podoplanin is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable

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