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Supelco

Cefquinome sulfate

VETRANAL®, analytical standard

Sinônimo(s):

(6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(5,6,7,8-tetrahydroquinolin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate sulfate, Cefquinome sulphate

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About This Item

Fórmula empírica (Notação de Hill):
C23H24N6O5S2 · H2SO4
Número CAS:
Peso molecular:
626.68
Beilstein:
11333438
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

linha de produto

VETRANAL®

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

forensics and toxicology
pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

OS([O-])(=O)=O.CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(C[n+]3cccc4CCCCc34)=C(N2C1=O)C(O)=O)c5csc(N)n5

InChI

1S/C23H24N6O5S2.H2O4S/c1-34-27-16(14-11-36-23(24)25-14)19(30)26-17-20(31)29-18(22(32)33)13(10-35-21(17)29)9-28-8-4-6-12-5-2-3-7-15(12)28;1-5(2,3)4/h4,6,8,11,17,21H,2-3,5,7,9-10H2,1H3,(H3-,24,25,26,30,32,33);(H2,1,2,3,4)/b27-16-;/t17-,21-;/m1./s1

chave InChI

KYOHRXSGUROPGY-OFNLCGNNSA-N

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Descrição geral

Cefquinome sulfates are veterinary, parenteral, fourth-generation cephalosporins belonging to the aminothiazolyl class of compounds. They exhibit broad-spectrum antimicrobial activity against gram-positive and gram-negative bacteria such as Pseudomonas aeruginosa and Enterobacteriaceae.

Aplicação

Cefquinome sulfate may be used as an analytical reference standard for the determination of the analyte in:
  • Pharmaceutical dosage form by reversed phase high performance liquid chromatography (RP-HPLC).


It may be used as a precursor for the preparation of cefquinome that can be employed as an analytical reference standard for the analysis of the analyte in:
  • Bovine milk as well as muscle and kidney samples by HPLC and LC coupled to tandem mass spectrometry (MS/MS), respectively.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informações legais

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3


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Residue analysis of 15 penicillins and cephalosporins in bovine muscle, kidney and milk by liquid chromatography-tandem mass spectrometry.
Becker M, et al.
Analytica Chimica Acta, 520(1-2), 19-32 (2004)
Dongbo Li et al.
Colloids and surfaces. B, Biointerfaces, 182, 110323-110323 (2019-07-20)
Staphylococcus aureus (S. aureus) has the propensity to form biofilms, which eventually cause antibiotic resistance and treatment failure. Cefquinome sulfate (CS) is an animal-specific antibacterial agent for S. aureus infection. In this work, CS cationic proliposomes (CSCPs) were prepared by
Determination of cephalosporins in raw bovine milk by high-performance liquid chromatography.
S?rensen LK and Snor LK
Journal of Chromatography A, 882(1-2), 145-151 (2000)
Aleksandar Siljanoski et al.
The Journal of dairy research, 85(3), 321-326 (2018-07-04)
The purpose of this study was to determine tetracycline and other antimicrobial residues in milk from dairy cows treated for clinical mastitis. Data on cow health and drugs used were obtained from the farm veterinarians. A milk sample from each
Ivana G Castilho et al.
Journal of dairy science, 100(8), 6414-6421 (2017-06-03)
Staphylococcus aureus is a common pathogen that causes subclinical bovine mastitis due to several virulence factors. In this study, we analyzed S. aureus isolates collected from the milk of cows with subclinical mastitis that had 8 possible combinations of bap

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