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Supelco

Arecoline hydrobromide

VETRANAL®, analytical standard

Sinônimo(s):

1-Methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid methyl ester hydrobromide, Arecaidine methyl ester hydrobromide, Methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide, Methyl 1-methyl-1,2,5,6-tetrahydronicotinate hydrobromide, Taeniolin

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About This Item

Fórmula empírica (Notação de Hill):
C8H13NO2 · HBr
Número CAS:
300-08-3
Peso molecular:
236.11
Beilstein:
3914826
Número CE:
206-087-3
Número MDL:
MFCD00039041
Código UNSPSC:
41116107
ID de substância PubChem:
329753838
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

linha de produto

VETRANAL®

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

172-176 °C (lit.)

aplicação(ões)

clinical
food and beverages

formato

neat

cadeia de caracteres SMILES

Br[H].COC(=O)C1=CCCN(C)C1

InChI

1S/C8H13NO2.BrH/c1-9-5-3-4-7(6-9)8(10)11-2;/h4H,3,5-6H2,1-2H3;1H

chave InChI

AXOJRQLKMVSHHZ-UHFFFAOYSA-N

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Descrição geral

Arecoline hydrobromide is an arecoline salt of hydrobromic acid generally used in removing parasites from dog′s intestine. It has a strong parasympathomimetic action.

Aplicação

Arecoline hydrobromide may have been used as working standard in the determination of arecoline concentration from dog plasma using LC–MS/MS.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informações legais

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302

Declarações de precaução

P264 - P270 - P301 + P312 - P501

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
BCCG1823
BCBT6367
BCBS1213V
SZBG005XV
SZBE092XV

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THE RELATION BETWEEN METHOD OF ADMINISTRATION, ROUTE OF ABSORPTION, INHIBITORY ACTIONS AND ACUTE TOXICITY OF ARECOLINE HYDROBROMIDE IN DOGS.
FORBES LS.
Annals of Tropical Medicine and Parasitology, 58, 119-131 (1964)
Sarah L Withey et al.
The Journal of pharmacology and experimental therapeutics, 366(2), 397-409 (2018-05-23)
Evidence suggests that the α4β2, but not the α7, subtype of the nicotinic acetylcholine receptor (nAChR) plays a key role in mediating the behavioral effects of nicotine and related drugs. However, the importance of other nAChR subtypes remains unclear. The
A Dakkak et al.
Acta tropica, 165, 26-32 (2016-07-21)
This study was undertaken in the Province of Sidi Kacem in northwest Morocco between April 2010 and March 2011. The main objective of the study was to determine the prevalence of Echinococcus granulosus (Eg) infection in owned dogs. This province
Osamu Uehara et al.
Oncology letters, 14(1), 1186-1192 (2017-07-12)
Betel quid chewing is implicated in the high prevalence of oral cancer in Southeast Asian countries. One of the major components of betel quid is arecoline. In the present study, in order to characterize the association between chronic arecoline stimulation
Vipin Jain et al.
Journal of agricultural and food chemistry, 65(9), 1977-1983 (2017-02-14)
Chewing of areca nut in different forms such as betel quid or commercially produced pan masala and gutkha is common practice in the Indian subcontinent and many parts of Asia and is associated with a variety of negative health outcomes
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