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AB9983

Sigma-Aldrich

Anti-Tyrosine Hydroxylase Antibody

from rabbit

Sinônimo(s):

Tyrosine 3-hydroxylase, tyrosine 3-monooxygenase, tyrosine hydroxylase

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

reatividade de espécies

rat, mouse

técnica(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

mouse ... Th(21823)
rat ... Th(25085)

Descrição geral

Tyrosine Hydroxylase plays an important role in the physiology of adrenergic neurons. It is the first and rate-limiting enzyme involved in the biosynthesis of the catecholamines Dopamine and Norepinephrine from tyrosine. TH is, therefore, a useful marker for dopaminergic and noradrenergic neurons. The enzymatic activity of TH requires ferrous ions as cofactors and is believed to be regulated by phosphorylation. At least four isoforms of human TH have been identified which result from alternative splicing.

Especificidade

Cat. # AB9983 recognizes the C-terminus of Tyrosine Hydroxylase
Reactivity with other species has not been determined.

Imunogênio

Epitope: C-terminus
Recombinant protein

Aplicação

Anti-Tyrosine Hydroxylase Antibody detects level of Tyrosine Hydroxylase & has been published & validated for use in IH(P) & WB.
Immunohistochemistry: 1:100 working dilutions were used on rat and mouse brain (paraffin embedded tissue).
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Descrição-alvo

~ 58 kDa

forma física

Antigen Affinity Purified
Format: Purified
Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3

Armazenamento e estabilidade

Stable for 1 year at 2-8ºC from date of receipt.

Nota de análise

Control
Rat Brain lysate

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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