572631

SU5402

InSolution, ≥95%, Inhibits the tyrosine kinase activity of FGFR1

• Sinônimo(s): InSolution SU5402
• Código UNSPSC: 12352200

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥95% (HPLC)
• forma: liquid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; desiccated (hygroscopic); protect from light
• temperatura de armazenamento: −70°C

Descrição

Descrição geral

Inhibits the tyrosine kinase activity of FGFR1 (IC₅₀ = 10-20 µM in the presence of 1 mM ATP) by interacting with the catalytic domain of FGFR1. Also inhibits aFGF-induced phosphorylation of ERK1 and ERK2 (IC₅₀ = 10-20 µM). In contrast to SU4984, it acts only as a weak inhibitor of tyrosine phosphorylation of the PDGF receptor. Does not inhibit the phosphorylation of insulin receptor and exhibits no inhibitory effect on EGF receptor kinase.

Embalagem

Packaged under inert gas

Advertência

Toxicity: Irritant (B)

forma física

A 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 572630) in DMSO.

Reconstituição

Following initial thaw, aliquot and freeze (-70°C).

Outras notas

Mohammadi, M., et al. 1997. Science 276, 955.

Informações legais

Not available for sale in the United States.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 188.6 °F - (refers to pure substance)
• Ponto de fulgor (°C): 87 °C - (refers to pure substance)