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Merck

VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

Sinônimos:
NR1I1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(7421) Summary: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
  • Mouse(22337) vitamin D receptor
  • Rat(24873) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • chicken(395988) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • dog(486588) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • Horse(100034072) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • domestic cat(100316614) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • cow(533656) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • sheep(101107273) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • sheep(100294603) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • naked mole-rat(101710294) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • domestic guinea pig(100734655) vitamin D (1,25- dihydroxyvitamin D3) receptor

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
Colecalciferol, ≥98% (HPLC),
Espécies
human
Colecalciferol (D3), analytical standard,
Espécies
human
Ergocalciferol, ≥98.0% (sum of enantiomers, HPLC),
Espécies
human
Vitamin D3 solution, 1 mg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human
25-Hydroxyvitamin D3 solution, 100 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
1α,25-di-hidrovitamina D3, ≥99% (HPLC),
Espécies
human
1α,25-di-hidrovitamina D3, ≥97.0% (HPLC),
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Vitamin D Receptor antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-VDR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
Anti-Vitamin D3 Receptor Antibody, clone 1M19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
bovine, canine, feline, human, monkey, mouse, porcine, rat
Aplicação
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-VDR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Monoclonal Anti-VDR antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunohistochemistry

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human VDR,
Espécies
human