UBB
ubiquitin B
Sinônimos:
Espécies:
Human UBB (7314), Mouse Ubb (22187), Rat Ubb (192255), cow UBB (281370), naked mole-rat Ubb (101702552), domestic guinea pig Ubb (100722422), Zebrafish ubb (550134), chicken UBB (396190), Horse UBB (100049794), domestic cat UBB (101091319)
ID UniProtKB:
ID do gene:
- Human(7314) Summary: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq, Jul 2008]
- Mouse(22187) ubiquitin B
- Rat(192255) ubiquitin B
- cow(281370) ubiquitin B
- naked mole-rat(101702552) ubiquitin B
- domestic guinea pig(100722422) ubiquitin B
- Zebrafish(550134) ubiquitin B
- chicken(396190) ubiquitin B
- Horse(100049794) ubiquitin B
- domestic cat(101091319) ubiquitin B
- dog(479513) ubiquitin B
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-phospho-Ubiquitin (Ser65), from rabbit, purified by affinity chromatography,
Reatividade de espécies
bovine, guinea pig, hamster, horse, human, mouse, nonhuman primates, rat, sheep
Aplicação
immunocytochemistry
western blot
western blot
Anti-Ubiquitin (pan) Antibody, clone 2G7B8, clone 2G7B8, from mouse,
Reatividade de espécies
human
Aplicação
western blot
Anti-Ubiquitin Lys63 Antibody, clone HWA4C4 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human
Aplicação
ELISA
affinity binding assay
western blot
affinity binding assay
western blot
Anti-Ubiquitin Rabbit pAb, liquid, Calbiochem®,
Reatividade de espécies
drosophila, e. coli, bovine, canine, chicken, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, sheep, yeast
Aplicação
Anti-phospho-Ubiquitin Antibody (Ser65), Alexa Fluor™ 488 Conjugate, from rabbit, ALEXA FLUOR™ 488,
Reatividade de espécies
bovine, guinea pig, hamster, horse, human, mouse, nonhuman primates, rat, sheep
Aplicação
immunocytochemistry