Pular para o conteúdo
MilliporeSigma

TTR

transthyretin

Sinônimos:
CTS, CTS1, HsT2651, PALB, TBPA
Espécies:
Human TTR (7276), Mouse Ttr (22139), Rat Ttr (24856), fruit fly ttr (246932), domestic cat TTR (101085927), dog TTR (480167), chicken TTR (396277), Zebrafish ttr (449556), cow TTR (280948), sheep TTR (443389) ...Mais
ID UniProtKB:
P02766, Q549C7, Q6IB96, Q9UBZ6, Q9UCM9
ID do gene:
  • Human(7276) Summary: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009]
  • Mouse(22139) transthyretin
  • Rat(24856) transthyretin
  • fruit fly(246932) tetrapter
  • domestic cat(101085927) transthyretin
  • dog(480167) transthyretin
  • chicken(396277) transthyretin
  • Zebrafish(449556) transthyretin (prealbumin, amyloidosis type I)
  • cow(280948) transthyretin
  • sheep(443389) transthyretin
  • domestic guinea pig(100735950) transthyretin
  • naked mole-rat(101726783) transthyretin

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Small Molecule - Antagonist

Número do produto
Descrição
Espécies
240834
Diphenyl ether, ReagentPlus®, ≥99%,
Espécies
human
W366706
Diphenyl ether, ≥99%, FG,
Espécies
human
144509
N-Phenylanthranilic acid, 98%,
Espécies
human
P24101
Diphenyl ether, ReagentPlus®, 99%,
Espécies
human
T2376
L-Thyroxine, ≥98% (HPLC),
Espécies
human, mouse, rat

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
HPA002550
Anti-TTR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
western blot
AMAB90649
Monoclonal Anti-TTR antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0290, purified immunoglobulin, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
SAB2501931
Anti-TTR antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
canine, human, mouse, rat
Aplicação
ELISA
immunohistochemistry
MAB10762
Anti-Transthyretin Antibody, clone 7G8-E11-E7, clone 7G8-E11-E7, from mouse,
Reatividade de espécies
human
Aplicação
ELISA
western blot
SAB3500378
Anti-Transthyretin antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Ligand

Número do produto
Descrição
Espécies
T2376
L-Thyroxine, ≥98% (HPLC),
Espécies
human, mouse, rat
T1775
L-Thyroxine, powder, BioReagent, suitable for cell culture,
Espécies
human, mouse, rat

Proteins

Número do produto
Descrição
Espécies
P1742
Prealbumin from human plasma, lyophilized powder,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EHU024621
MISSION® esiRNA, targeting human TTR,
Espécies
human
EMU030721
MISSION® esiRNA, targeting mouse Ttr,
Espécies
mouse