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Merck

TNNI3

troponin I type 3 (cardiac)

Sinônimos:
CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI
Espécies:
Human TNNI3 (7137), Mouse Tnni3 (21954), Rat Tnni3 (29248), chicken TNNI3 (396428), domestic cat TNNI3 (493744), Horse TNNI3 (100034065), dog TNNI3 (403566), sheep TNNI3 (101121961), domestic guinea pig Tnni3 (100718375), naked mole-rat Tnni3 (101711288)
ID UniProtKB:
P19429
ID do gene:
  • Human(7137) Summary: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
  • Mouse(21954) troponin I, cardiac 3
  • Rat(29248) troponin I type 3 (cardiac)
  • chicken(396428) troponin I type 3 (cardiac)
  • domestic cat(493744) troponin I type 3 (cardiac)
  • Horse(100034065) troponin I type 3 (cardiac)
  • dog(403566) troponin I type 3 (cardiac)
  • sheep(101121961) troponin I type 3 (cardiac)
  • domestic guinea pig(100718375) troponin I type 3 (cardiac)
  • naked mole-rat(101711288) troponin I type 3 (cardiac)

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ELISA

Product Number
Descrição
Espécies
RAB0634
Human TNNI3 / Troponin I, Cardiac Muscle ELISA Kit, ,
Espécies
human

Small Molecule - Allosteric Modulator

Product Number
Descrição
Espécies
L5545
Levosimendan, ≥98% (HPLC),
Espécies
human

Antibodies

Product Number
Descrição
Reatividade de espécies
Aplicação
HPA046428
Anti-TNNI3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
WH0007137M4
Monoclonal Anti-TNNI3 antibody produced in mouse, clone 1E7, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence
western blot
MABT546
Anti-Troponin I Antibody, clone 5C11.1, clone 5C11.1, from mouse,
Reatividade de espécies
bovine, chicken, human, mouse, rat
Aplicação
western blot
SAB4502991
Anti-TNNI3 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry
western blot
SAB4502990
Anti-Tnni3, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
mouse, rat
Aplicação
ELISA
immunofluorescence
immunohistochemistry
western blot

Proteins

Product Number
Descrição
Espécies
T9924
Troponin I from human heart, lyophilized powder,
Espécies
human

esiRNA

Product Number
Descrição
Espécies
EHU022131
MISSION® esiRNA, targeting human TNNI3,
Espécies
human
EMU068451
MISSION® esiRNA, targeting mouse Tnni3,
Espécies
mouse