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Merck

TLR9

toll-like receptor 9

Sinônimos:
CD289
Espécies:
ID UniProtKB:
ID do gene:
  • Human(54106) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
  • Mouse(81897) toll-like receptor 9
  • Rat(338457) toll-like receptor 9
  • Zebrafish(403128) toll-like receptor 9
  • domestic cat(493839) toll-like receptor 9
  • Horse(100009693) toll-like receptor 9
  • dog(403502) toll-like receptor 9
  • cow(282602) toll-like receptor 9
  • sheep(494547) toll-like receptor 9
  • Goat(100860819) toll-like receptor 9
  • naked mole-rat(101715478) toll-like receptor 9

Custom & Knockdown Gene Products

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Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Sulfato de hidroxicloroquina, ≥98% (HPLC), powder,
Espécies
human
Sulfato de hidroxicloroquina, British Pharmacopoeia (BP) Reference Standard,
Espécies
human
2-((4-(7-Chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol, ,
Espécies
human
Sulfato de hidroxicloroquina, British Pharmacopoeia (BP) Reference Standard,
Espécies
human
Sulfato de hidroxicloroquina, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-TLR9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-TLR9 antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence

western blot
ANTI-TLR9 antibody produced in mouse, clone 2H5, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
ANTI-TLR9 antibody produced in mouse, clone 2G3, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Anti-TLR9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, goat, horse, human, pig, sheep
Aplicação
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human TWF2, RP11-330H6.5,
Espécies
human
MISSION® esiRNA, targeting human TLR9, RP11-330H6.5,
Espécies
human