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Merck

SRC

v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Sinônimos:
ASV, SRC1, c-SRC, p60-Src
Espécies:
Human SRC (6714), Mouse Src (20779), Rat Src (83805), cow SRC (535742), sheep SRC (101103084), naked mole-rat Src (101703827), domestic guinea pig Src (100728509), Zebrafish src (325084), domestic cat SRC (101100378), dog SRC (485864)
ID UniProtKB:
P12931, E1P5V4, Q76P87, Q86VB9, Q9H5A8
ID do gene:
  • Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20779) Rous sarcoma oncogene
  • Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic guinea pig(100728509) Rous sarcoma oncogene
  • Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • chicken(396442) v-src sarcoma viral oncogene

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Small Molecule - Antagonist

Número do produto
Descrição
Espécies
695017
Ácido fosfórico, ACS reagent, ≥85 wt. % in H2O,
Espécies
human
345245
Ácido fosfórico, 85 wt. % in H2O, 99.99% trace metals basis,
Espécies
human
438081
Ácido fosfórico, ACS reagent, ≥85 wt. % in H2O,
Espécies
human
30417
Ácido fosfórico, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥85%,
Espécies
human
27109
Ácido cítrico, meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance),
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
05-677
Anti-phospho-Src (Tyr416) Antibody, clone 9A6, clone 9A6, Upstate®, from mouse,
Reatividade de espécies
human, mouse
Aplicação
immunoprecipitation (IP)
western blot
07-909
Anti-phospho-Src (Tyr418) Antibody, Upstate®, from rabbit,
Reatividade de espécies
chicken, human, mouse
Aplicação
immunocytochemistry
immunohistochemistry
western blot
HPA030875
Anti-SRC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
SAB5300367
Monoclonal Anti-SRC antibody produced in mouse, clone 1F11, ascites fluid,
Reatividade de espécies
human
Aplicação
ELISA
flow cytometry
immunohistochemistry
western blot
04-772
Anti-Src Antibody, CT, clone NL19 | 04-772, clone NL19, Upstate®, from rabbit,
Reatividade de espécies
human, mouse, rat
Aplicação
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
S9692
SU 6656, ≥98% (HPLC),
Espécies
human
R2146
Radicicol from Diheterospora chlamydosporia, solid,
Espécies
human, rat
PZ0192
Bosutinib, ≥98% (HPLC),
Espécies
human
E2250
Ellagic acid, ≥95% (HPLC), powder, from tree bark,
Espécies
human, rat
T182
Tyrphostin A9, solid,
Espécies
mouse, human

Kits

Número do produto
Descrição
Espécies
20-121
Src Kinase Reaction Buffer, ,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
14-326-M
Src Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Espécies
human
S1076
SRC, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human
14-748-M
Src (T341M) Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Espécies
human
S5564
SRC N1 human, ≥60% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Espécies
human
14-746-M
Src (1-530) Protein, active, 10 µg, ,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EMU071351
MISSION® esiRNA, targeting mouse Src,
Espécies
mouse

Small Molecule - Substrate

Número do produto
Descrição
Espécies
12-140
Src Substrate Peptide, Src Substrate Peptide primarily used in Kinase Assays.,
Espécies
human