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Merck

SET

SET nuclear oncogene

Sinônimos:
2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA
Espécies:
Human SET (6418), Mouse Set (56086), Rat Set (307947), fruit fly Set (41844), domestic cat SET (101081583), dog SET (608952), chicken SET (417210), cow SET (538444), sheep SET (101118680), naked mole-rat Set (101720656)
ID UniProtKB:
Q01105, A5A5H4, A6NGV1, B4DUE2, Q15541, Q5VXV1, Q5VXV2, Q6FHZ5
ID do gene:
  • Human(6418) Summary: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
  • Mouse(56086) SET nuclear oncogene
  • Rat(307947) SET nuclear oncogene
  • fruit fly(41844) CG4299 gene product from transcript CG4299-RA
  • domestic cat(101081583) SET nuclear oncogene
  • dog(608952) SET nuclear oncogene
  • chicken(417210) SET nuclear oncogene
  • cow(538444) SET nuclear oncogene
  • sheep(101118680) SET nuclear oncogene
  • naked mole-rat(101720656) SET nuclear oncogene
  • domestic guinea pig(100715138) SET nuclear oncogene

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
HPA063683
Anti-SET antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
western blot
SAB2104853
Anti-SET, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
immunohistochemistry
immunoprecipitation (IP)
western blot
MABN1857
Anti-SET-beta, clone 3D10E2, clone 3D10E2, from mouse,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
MABN1863
Anti-SET-alpha, clone 5F4D9, clone 5F4D9, from mouse,
Reatividade de espécies
human
Aplicação
western blot
ABN1738
Anti-SET-beta Antibody, serum, from rabbit,
Reatividade de espécies
bovine, human, mouse, rat
Aplicação
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot

esiRNA

Número do produto
Descrição
Espécies
EMU158271
MISSION® esiRNA, targeting mouse Set,
Espécies
mouse