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Merck

POLD2

polymerase (DNA directed), delta 2, accessory subunit

Sinônimos:
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5425) Summary: This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]
  • Mouse(18972) polymerase (DNA directed), delta 2, regulatory subunit
  • Rat(289758) polymerase (DNA directed), delta 2, accessory subunit
  • Thale Cress(818812) DNA polymerase delta subunit 2
  • Zebrafish(796456) polymerase (DNA directed), delta 2, regulatory subunit
  • domestic cat(101095089) polymerase (DNA directed), delta 2, accessory subunit
  • dog(482686) polymerase (DNA directed), delta 2, accessory subunit
  • chicken(100859398) polymerase (DNA directed), delta 2, accessory subunit
  • cow(281991) polymerase (DNA directed), delta 2, regulatory subunit 50kDa
  • sheep(101117838) polymerase (DNA directed), delta 2, accessory subunit
  • domestic guinea pig(100727561) polymerase (DNA directed), delta 2, accessory subunit
  • naked mole-rat(101722261) polymerase (DNA directed), delta 2, accessory subunit
  • Domestic Rabbit(100358263) polymerase (DNA directed), delta 2, accessory subunit

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Antibodies

Product Number
Descrição
Reatividade de espécies
Aplicação
Anti-DNA polymerase δ p50 antibody, Rat monoclonal, clone PDK 7B4, purified from hybridoma cell culture,
Reatividade de espécies
human
Aplicação
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-POLD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-POLD2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot

Small Molecule - Inhibitor

Product Number
Descrição
Espécies
Cytosine β-D-arabinofuranoside hydrochloride, crystalline,
Espécies
human
Cytarabine, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Cytarabine, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Cytarabine, British Pharmacopoeia (BP) Reference Standard,
Espécies
human
Cytosine β-D-arabinofuranoside, crystalline, ≥90% (HPLC),
Espécies
human, mouse

esiRNA

Product Number
Descrição
Espécies
MISSION® esiRNA, targeting human POLD2,
Espécies
human
MISSION® esiRNA, targeting mouse Pold2,
Espécies
mouse