PML
promyelocytic leukemia
Sinônimos:
MYL, PP8675, RNF71, TRIM19
Espécies:
Human PML (5371), Mouse Pml (18854), Rat Pml (315713), chicken PML (415302), chicken PML (415304), Horse PML (100062744), domestic cat PML (101086975), dog PML (487641), cow PML (100138545), sheep PML (101111580) ...Mais
ID UniProtKB:
ID do gene:
- Human(5371) Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(18854) promyelocytic leukemia
- Rat(315713) promyelocytic leukemia
- chicken(415302) promyelocytic leukemia
- chicken(415304) promyelocytic leukemia
- Horse(100062744) promyelocytic leukemia
- domestic cat(101086975) promyelocytic leukemia
- dog(487641) promyelocytic leukemia
- cow(100138545) promyelocytic leukemia
- sheep(101111580) promyelocytic leukemia
- naked mole-rat(101707749) promyelocytic leukemia
- domestic guinea pig(100720832) promyelocytic leukemia
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PML Antibody, clone 36.1-104, clone 36.1-104, Upstate®, from mouse,
Reatividade de espécies
mouse
Aplicação
immunocytochemistry
western blot
western blot
Anti-PML antibody, Mouse monoclonal, clone PML-97, purified from hybridoma cell culture,
Reatividade de espécies
hamster, human, mouse
Aplicação
ELISA
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot
Rabbit anti-PML Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reatividade de espécies
human
Aplicação
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-PML Isoform II Antibody, clone 1A8.1, clone 1A8.1, from mouse,
Reatividade de espécies
human
Aplicação
immunocytochemistry
western blot
western blot
Anti-PML Antibody, clone 1F13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human, mouse, rat
Aplicação
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot