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Merck

OTUD5

OTU domain containing 5

Sinônimos:
DUBA
Espécies:
ID UniProtKB:
ID do gene:
  • Human(55593) Summary: This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]
  • Mouse(54644) OTU domain containing 5
  • Rat(363452) OTU domain containing 5
  • cow(539145) OTU domain containing 5
  • domestic cat(101098283) OTU domain containing 5
  • dog(480911) OTU domain containing 5
  • sheep(101106912) OTU domain containing 5
  • naked mole-rat(101712863) OTU domain containing 5
  • domestic guinea pig(100732793) OTU domain containing 5

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-OTUD5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
Anti-OTUD5 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human OTUD5,
Espécies
human
MISSION® esiRNA, targeting mouse Otud5,
Espécies
mouse