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Merck

NR3C2

nuclear receptor subfamily 3, group C, member 2

Sinônimos:
MCR, MLR, MR, NR3C2VIT
Espécies:
ID UniProtKB:
ID do gene:
  • Human(4306) Summary: This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • Mouse(110784) nuclear receptor subfamily 3, group C, member 2
  • Rat(25672) nuclear receptor subfamily 3, group C, member 2
  • Zebrafish(562171) nuclear receptor subfamily 3, group C, member 2
  • dog(475461) nuclear receptor subfamily 3, group C, member 2
  • cow(280861) nuclear receptor subfamily 3, group C, member 2
  • cow(537614) nuclear receptor subfamily 3, group C, member 2
  • Horse(100062570) nuclear receptor subfamily 3, group C, member 2
  • domestic cat(101081977) nuclear receptor subfamily 3, group C, member 2
  • chicken(374131) nuclear receptor subfamily 3, group C, member 2
  • sheep(101107046) nuclear receptor subfamily 3, group C, member 2
  • domestic guinea pig(100735309) nuclear receptor subfamily 3, group C, member 2

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
Deoxycorticosterone acetate, ,
Espécies
human
Fludrocortisone acetate, ≥98%,
Espécies
human
Fludrocortisone acetate, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Fludrocortisone acetate, British Pharmacopoeia (BP) Reference Standard,
Espécies
human
Drospirenone, ≥98% (HPLC),
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Eplerenone, ≥98% (HPLC),
Espécies
human
Canrenone, ≥97% (HPLC),
Espécies
human
Spironolactone, British Pharmacopoeia (BP) Reference Standard,
Espécies
human
Spironolactone, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Canrenone, European Pharmacopoeia (EP) Reference Standard,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anticorpo antirreceptor de mineralocorticoide, clone 6G1, clone 6G1, from mouse,
Reatividade de espécies
mouse, rat
Aplicação
immunocytochemistry
immunohistochemistry

western blot
Anti-NR3C2 antibody produced in rabbit, IgG fraction of antiserum,
Reatividade de espécies
human, rabbit
Aplicação
immunohistochemistry
western blot
Anti-Mineralocorticoid Receptor Antibody, clone 2D6, clone 2D6, from mouse,
Reatividade de espécies
rat
Aplicação
immunocytochemistry
immunohistochemistry

western blot
Anti-NR3C2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-NR3C2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
horse, human
Aplicação
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human NR3C2,
Espécies
human
MISSION® esiRNA, targeting mouse Nr3c2,
Espécies
mouse