IL6R
interleukin 6 receptor
Sinônimos:
CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Espécies:
Human IL6R (3570), Rat Il6r (24499), Zebrafish il6r (100135755), cow IL6R (507359), domestic cat IL6R (101085689), dog IL6R (612271), domestic guinea pig Il6r (100730490), naked mole-rat Il6r (101704925), sheep IL6R (101103369)
ID UniProtKB:
ID do gene:
- Human(3570) Summary: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
- Rat(24499) interleukin 6 receptor
- Zebrafish(100135755) interleukin 6 receptor
- cow(507359) interleukin 6 receptor
- domestic cat(101085689) interleukin 6 receptor
- dog(612271) interleukin 6 receptor
- domestic guinea pig(100730490) interleukin 6 receptor
- naked mole-rat(101704925) interleukin 6 receptor
- sheep(101103369) interleukin 6 receptor
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Monoclonal Anti-IL6R antibody produced in mouse, clone 1E11, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
western blot
Anti-IL-6R Antibody, clone 1D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human, monkey
Aplicação
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-IL6R antibody produced in mouse, clone 2G6, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
western blot
Anti-IL6R antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Proteins
Número do produto
Descrição
Espécies
sIL-6 Receptor alpha human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Espécies
human
esiRNA
Número do produto
Descrição
Espécies