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Merck

HNMT

histamine N-methyltransferase

Sinônimos:
HMT, HNMT-S1, HNMT-S2
Espécies:
Human HNMT (3176), Mouse Hnmt (140483), Rat Hnmt (81676), sheep HNMT (101102876), sheep HNMT (641310), domestic guinea pig Hnmt (100135537), Zebrafish hnmt (445242), dog HNMT (476133), cow HNMT (613413), domestic cat HNMT (101093704)
ID UniProtKB:
P50135, B2R9J3, Q546Z6, Q7Z7I2, Q8IU56, Q8WW98, Q9BRW6
ID do gene:
  • Human(3176) Summary: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(140483) histamine N-methyltransferase
  • Rat(81676) histamine N-methyltransferase
  • sheep(101102876) histamine N-methyltransferase
  • sheep(641310) histamine N-methyltransferase
  • domestic guinea pig(100135537) histamine N-methyltransferase
  • Zebrafish(445242) histamine N-methyltransferase
  • dog(476133) histamine N-methyltransferase
  • cow(613413) histamine N-methyltransferase
  • domestic cat(101093704) histamine N-methyltransferase
  • chicken(424298) histamine N-methyltransferase

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
HPA035481
Anti-HNMT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
HPA035480
Anti-HNMT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
SAB1410643
Anti-HNMT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
HPA073754
Anti-HNMT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot

esiRNA

Número do produto
Descrição
Espécies
EHU092321
MISSION® esiRNA, targeting human HNMT (1),
Espécies
human
EHU135431
MISSION® esiRNA, targeting human HNMT (3),
Espécies
human
EHU099901
MISSION® esiRNA, targeting human HNMT (2),
Espécies
human