HIRA
histone cell cycle regulator
Sinônimos:
DGCR1, TUP1, TUPLE1
Espécies:
Human HIRA (7290), Mouse Hira (15260), Rat Hira (363849), Zebrafish hira (568076), fruit fly Hira (31680), cow HIRA (511514), Horse HIRA (100052845), domestic cat HIRA (101098170), dog HIRA (486424), Thale Cress HIRA (823578) ...Mais
ID UniProtKB:
ID do gene:
- Human(7290) Summary: This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
- Mouse(15260) histone cell cycle regulation defective homolog A (S. cerevisiae)
- Rat(363849) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Zebrafish(568076) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- fruit fly(31680) CG12153 gene product from transcript CG12153-RA
- cow(511514) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Horse(100052845) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- domestic cat(101098170) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- dog(486424) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Thale Cress(823578) protein HIRA
- chicken(374074) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- sheep(101120607) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Domestic Rabbit(100352472) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-HIRA Antibody, clone WC119, clone WC119, from mouse,
Reatividade de espécies
human, mouse
Aplicação
immunoprecipitation (IP)
western blot
western blot
Anti-HIRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-HIRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-HIRA (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
western blot
Anti-HIRA antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
western blot