HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
Sinônimos:
DFNB39, F-TCF, HGFB, HPTA, SF
Espécies:
Human HGF (3082), Mouse Hgf (15234), Rat Hgf (24446), domestic guinea pig Hgf (100730730), naked mole-rat Hgf (101707056), sheep HGF (443075), Domestic Rabbit HGF (100316908), chicken HGF (395941), cow HGF (282879), domestic cat HGF (493705)
ID UniProtKB:
ID do gene:
- Human(3082) Summary: Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(15234) hepatocyte growth factor
- Rat(24446) hepatocyte growth factor
- domestic guinea pig(100730730) hepatocyte growth factor (hepapoietin A; scatter factor)
- naked mole-rat(101707056) hepatocyte growth factor (hepapoietin A; scatter factor)
- sheep(443075) hepatocyte growth factor (hepapoietin A; scatter factor)
- Domestic Rabbit(100316908) hepatocyte growth factor (hepapoietin A; scatter factor)
- chicken(395941) hepatocyte growth factor (hepapoietin A; scatter factor)
- cow(282879) hepatocyte growth factor (hepapoietin A; scatter factor)
- domestic cat(493705) hepatocyte growth factor (hepapoietin A; scatter factor)
- dog(403441) hepatocyte growth factor (hepapoietin A; scatter factor)
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ELISA
Número do produto
Descrição
Espécies
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-HGF antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, horse, human, mouse, pig, rabbit, rat
Aplicação
western blot
Anti-HGF (ab2) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, horse, human, mouse, pig, rabbit, rat, sheep
Aplicação
immunohistochemistry
western blot
western blot
Anti-HGF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-HGF antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human, mouse
Aplicação
proximity ligation assay
western blot
western blot
Anti-c-Met Antibody, clone seeMet 13, clone seeMet 13, from mouse,
Reatividade de espécies
human
Aplicação
flow cytometry
immunocytochemistry
immunoprecipitation (IP)
inhibition assay
immunocytochemistry
immunoprecipitation (IP)
inhibition assay
Proteins
Número do produto
Descrição
Espécies
Hepatocyte Growth Factor human, HGF, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
Espécies
human
Hepatocyte Growth Factor human, HGF, recombinant, expressed in NSO cells, suitable for cell culture,
Espécies
human
Hepatocyte Growth Factor human, HGF, recombinant, expressed in Baculovirus infected High-5 cells, suitable for cell culture,
Espécies
human
HGF mouse, recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE), ≥95% (HPLC),
Espécies
mouse