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Merck

GZMB

granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

Sinônimos:
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Espécies:
Human GZMB (3002), Mouse Gzmb (14939), Rat Gzmb (171528), dog GZMB (490630), cow GZMB (508646), cow GZMB (281731), Horse GZMB (100033978), domestic cat GZMB (100127106), domestic guinea pig Gzmb (100736180), naked mole-rat Gzmb (101702156)
ID UniProtKB:
P10144, Q8N1D2, Q9UCC1
ID do gene:
  • Human(3002) Summary: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]
  • Mouse(14939) granzyme B
  • Rat(171528) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • dog(490630) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • cow(508646) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • cow(281731) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • Horse(100033978) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • domestic cat(100127106) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • domestic guinea pig(100736180) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • naked mole-rat(101702156) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

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ELISA

Número do produto
Descrição
Espécies
RAB0210
Mouse Granzyme B ELISA Kit, for serum, plasma and cell culture supernatant,
Espécies
mouse
RAB1498
Human Granzyme B ELISA, for serum, plasma and cell culture supernatants,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
MAB3070
Anti-Granzyme B Antibody, clone GrB-7, culture supernatant, clone GrB-7, Chemicon®,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
ZRB2736
Anti-Granzyme B Antibody, clone 3M4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human
Aplicação
ELISA
affinity binding assay
flow cytometry
western blot
HPA003418
Anti-GZMB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
SAB4700295
Monoclonal Anti-GZMB antibody produced in mouse, clone CLB-GB11, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human, nonhuman primates
Aplicação
flow cytometry
SAB4501359
Anti-Granzyme B antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry
western blot

Proteins

Número do produto
Descrição
Espécies
SRE0021
Granzyme B human, recombinant, expressed in insect cells, ≥90% (SDS-PAGE),
Espécies
human
SRP3202
Granzyme B from mouse, recombinant, expressed in Hi-5 Insect cells, ≥97% (SDS-PAGE), ≥97% (HPLC), suitable for cell culture,
Espécies
mouse

esiRNA

Número do produto
Descrição
Espécies
EHU106641
MISSION® esiRNA, targeting human GZMB,
Espécies
human

Small Molecule - Substrate

Número do produto
Descrição
Espécies
A6470
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide, ≥97% (HPLC), powder,
Espécies
rat, mouse, human
A9968
N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide, ≥95%,
Espécies
rat, mouse, human
A6220
N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin, ≥97% (HPLC), powder,
Espécies
rat, mouse, human
A4188
N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, ≥97% (HPLC), powder,
Espécies
rat, mouse, human