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Merck

DDC

dopa decarboxylase (aromatic L-amino acid decarboxylase)

Sinônimos:
AADC
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1644) Summary: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
  • Mouse(13195) dopa decarboxylase
  • Rat(24311) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic guinea pig(100135516) dopa decarboxylase
  • naked mole-rat(101697555) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • sheep(101106765) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Zebrafish(406651) dopa decarboxylase
  • chicken(420947) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • fruit fly(35190) Dopa decarboxylase
  • dog(606852) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • cow(280762) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Horse(100052557) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic cat(101082989) dopa decarboxylase (aromatic L-amino acid decarboxylase)

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ELISA

Número do produto
Descrição
Espécies
Human Dopa Decarboxylase ELISA, for serum, plasma and cell culture supernatants,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-DDC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-Dopa Decarboxylase Antibody, Chemicon®, from rabbit,
Reatividade de espécies
canine, human, sheep
Aplicação
western blot
Monoclonal Anti-DDC antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2962, purified immunoglobulin, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-DDC antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
guinea pig, human, mouse, rat
Aplicação
western blot
Anti-DDC antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Benserazide hydrochloride, ≥98% (HPLC), solid,
Espécies
human
S-(−)-Carbidopa, ≥98% (TLC), powder,
Espécies
human
Carbidopa, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Benserazide for peak identification A, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Carbidopa, European Pharmacopoeia (EP) Reference Standard,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Ddc,
Espécies
mouse